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What’s the point in restaurant calorie counts?

More than a third of US adults are obese according to data from the Centers for Disease Control and Prevention and the associated medical costs are high. In this US editor’s choice, Edward Davies...

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Has pancreatic damage from glucagon suppressing diabetes drugs been underplayed?

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Helping patients make sense of the risks of taking GLP-1 agonists

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Incretin therapy: should adverse consequences have been anticipated?

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Incretins and risk of neoplasia

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Pfizer versus Kaiser: insurers want their day in court

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YODA and truth seeking in medicine

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Are clinical trial data shared sufficiently today? Yes

The AllTrials campaign asks for all trials to be registered and their results published. Ben Goldacre says we need the evidence to make informed decisions about medicines. John Castellani says...

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Does adding routine antibiotics to animal feed pose a serious risk to human...

As fears rise over resistance, some countries have banned routine use of antibiotics in animal feed. David Wallinga says a ban is possible without damaging food productivity, but David G S Burch argues...

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Should the FDA regulate mobile medical apps?

Bradley Merrill Thompson says regulation of certain medical apps is essential for patient safety, but Ira Brodsky believes unfettered development could see the reinvention of healthcare.

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Intravenous iron therapy for treatment of anaemia

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What to do about unsafe medicines?

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Humanism in the time of metrics—an essay by David Loxterkamp

Doctors’ increasing focus on biomarkers and measures of performance has shifted our attention away from what may be most important for our patients, argues David Loxterkamp.

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Taming the monster

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Investigating the fallout of a suicide

In 2004 Dan Markingson committed suicide while he was taking part in the CAFE psychiatric trial. After years of pressure and countless fruitless personal and legal battles, campaigners still believe...

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How to access and process FDA drug approval packages for use in research

FDA databases contain valuable information on unpublished studies, but it can be difficult to find. This article explains where to look and provides tips on how to make documents easier to use.

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Energy drinks: cause for concern or scaremongering?

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Severe hypotension associated with α blocker tamsulosin

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Bare metal stents, durable polymer drug eluting stents, and biodegradable...

According to this mixed treatment comparison meta-analysis, biodegradable polymer drug eluting stents are superior to first generation durable polymer drug eluting stents in reducing restenosis, but...

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Dunk that cola

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